A prospective randomized trial of vagotomy in chronic duodenal ulceration: 4-year follow-up-Reference-Cited by-同舟云学术

A prospective randomized trial of vagotomy in chronic duodenal ulceration: 4-year follow-up

Published:1983-06 Issue:6 Volume:70 Page:342-345
ISSN:0007-1323
Container-title:British Journal of Surgery
language:en
Short-container-title:

Author:

Koffman C G¹²,Hay D J¹²,Ganguli P C¹²,Elder J B¹²,Gillespie I E¹²,Mantoudis S M¹²,Tweedle D E F¹²,Schofield P F¹²,Palmer M¹²

Affiliation:

1. University Departments of Surgery. The Royal Infirmary, Oxford Road, Manchester M13 9WL

2. The University Hospital of South Manchester, Nell Lane, Manchester M20 8LE

Abstract

Abstract A total of 153 patients (124 male and 29 female) with uncomplicated chronic duodenal ulceration were studied in a prospective, randomized trial of proximal gastric vagotomy (PGV) and truncal vagotomy and pyloroplasty (TVP), conducted in four Manchester hospitals. Of these, 137 patients have now been followed up for 2·5 to 5·5 (mean 4·1) yr. There have been 15 (21 per cent) recurrent ulcers following PGV compared with 5 (7·5 per cent) after TVP (P < 0·05). A satisfactory functional result was obtained in 82 per cent of patients after TVP compared with 73 per cent following PGV and there was little difference between the groups with regard to the incidence of dumping, heartburn and vomiting. There was significantly more diarrhoea following TVP (13 per cent) compared to PGV (1·4 per cent) but this represented only a minor clinical problem.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Link

http://academic.oup.com/bjs/article-pdf/70/6/342/36933518/bjs1800700611.pdf

Reference20 articles.

1. Selective, highly selective, or truncal vagotomy;Johnson;Surg. Clin. North Am.,1976

2. Five to eight-year results of Leeds/York controlled trial of elective surgery for duodenal ulcer;Goligher;Br. Med. J.,1968

3. Selective or truncal vagotomy? Five year results of a double-blind, randomized controlled trial;Kennedy;Br. J. Surg.,1973

4. Highly selective vagotomy without a drainage procedure in the treatment of duodenal ulcer;Johnston;Br. J. Surg.,1970

5. Selective vagotomy of the parietal cell mass preserving innervation of the undrained antrum;Amdrup;Gastroenterology,1970

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