1. School of Chemical Engineering and Technology; Tianjin University; Tianjin 300072 China
2. Tianjin Key Laboratory of Molecular Design and Drug Discovery; Tianjin Institute of Pharmaceutical Research; Tianjin 300193 China
3. Graduate School of Tianjin Medical University; Tianjin 300070 China
4. State Key Laboratory of Drug Delivery Technology and Pharmacokinetics; Tianjin Institute of Pharmaceutical Research; Tianjin 300193 China