Commissioning and clinical evaluation of a novel high‐resolution quality assurance digital detector array for SRS and SBRT

Author:

Zhou Yang12,Liu Yimei1,Chen Meining1,Fang Jianlan1,Xiao Liangjie1,Huang Shaomin1,Qi Zhenyu1,Deng Xiaowu1ORCID,Zhang Jun1,Peng Yinglin1ORCID

Affiliation:

1. State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer Sun Yat‐sen University Cancer Center Guangzhou P. R. China

2. Department of Radiation Oncology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine Central South University Zhuzhou P. R. China

Abstract

AbstractPurposeWe aimed to perform the commissioning and clinical evaluation of myQA SRS detector array for patient‐specific quality assurance (PSQA) of stereotactic radiosurgery (SRS)/ stereotactic body radiotherapy (SBRT) plans.MethodsTo perform the commissioning of myQA SRS, its dose linearity, dose‐rate dependence, angular dependence, and field‐size dependence were investigated. Ten SBRT plans were selected for clinical evaluation: 1) Common clinical deviations based on the original SBRT plan (Plan0), including multileaf collimator (MLC) positioning deviation and treatment positioning deviation were introduced. 2) Compared the performance of the myQA SRS and a high‐resolution EPID dosimetry system in PSQA measurement for the SBRT plans. Evaluation parameters include gamma passing rate (GPR) and distance‐to‐agreement (DTA) pass rate (DPR).ResultsThe dose linearity, angle dependence, and field‐size dependence of myQA SRS system exhibit excellent performance. The myQA SRS is highly sensitive in the detection of MLC deviations. The GPR of (3%/1 mm) decreases from 90.4% of the original plan to 72.7%/62.9% with an MLC outward/inward deviation of 3 mm. Additionally, when the setup error deviates by 1 mm in the X, Y, and Z directions with the GPR of (3%/1 mm) decreasing by an average of −20.9%, −25.7%, and −24.7%, respectively, and DPR (1 mm) decreasing by an average of −33.7%, −32.9%, and −29.8%. Additionally, the myQA SRS has a slightly higher GPR than EPID for PSQA, However, the difference is not statistically significant with the GPR of (3%/1 mm) of (average 90.4%% vs. 90.1%, p = 0.414).ConclusionDosimetry characteristics of the myQA SRS device meets the accuracy and sensitivity requirement of PSQA for SRS/SBRT treatment. The dose rate dependence should be adequately calibrated before its application and a more stringent GPR (3%/1 mm) evaluation criterion is suggested when it is used for SRS/SBRT QA.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Wiley

Subject

Radiology, Nuclear Medicine and imaging,Instrumentation,Radiation

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