Affiliation:
1. Department of Computer Science University of Kentucky Lexington Kentucky USA
2. Department of Medicine‐Nephrology University of Alabama at Birmingham Birmingham Alabama USA
3. Department of Radiology University of Kentucky Lexington Kentucky USA
Abstract
AbstractWith the ever‐increasing use of computed tomography (CT), concerns about its radiation dose have become a significant public issue. To address the need for radiation dose reduction, CT denoising methods have been widely investigated and applied in low‐dose CT images. Numerous noise reduction algorithms have emerged, such as iterative reconstruction and most recently, deep learning (DL)‐based approaches. Given the rapid advancements in Artificial Intelligence techniques, we recognize the need for a comprehensive review that emphasizes the most recently developed methods. Hence, we have performed a thorough analysis of existing literature to provide such a review. Beyond directly comparing the performance, we focus on pivotal aspects, including model training, validation, testing, generalizability, vulnerability, and evaluation methods. This review is expected to raise awareness of the various facets involved in CT image denoising and the specific challenges in developing DL‐based models.
Funder
National Center for Research Resources
National Center for Advancing Translational Sciences
National Institutes of Health
National Science Foundation