Synthesis and Characterization of Polydopamine‐Modified Montmorillonite Loaded with Silver Nanoparticles for Antibacterial Functionalization

Author:

Wang Huiyan1,Huang Xinrong1,Liang Han1,Sun Xuemei1,Meng Na1ORCID,Zhou Ninglin234

Affiliation:

1. School of Food Science and Pharmaceutical Engineering Nanjing Normal University Nanjing 210046 China

2. Jiangsu Collaborative Innovation Center for Biological Functional Materials, College of Chemistry and Materials Science Nanjing Normal University Nanjing 210023 China

3. Jiangsu Key Laboratory of Biofunctional Materials Jiangsu Engineering Research Center for Biomedical Function Materials Nanjing 210023 China

4. Nanjing Zhou Ninglin Advanced Materials Technology Company Limited Nanjing 211505 China

Abstract

AbstractSince the development of bacterial resistance towards antibiotics has the potential to limit the effectiveness of antibiotics in the treatment of infectious diseases, it is necessary to try different strategies to provide alternatives. In order to solve the problems, this work used silver nanoparticles‐loaded polydopamine‐modified montmorillonite (AgNP/PDA−Mt) to cope with the infection of the gram‐negative bacteria Escherichia. Coli and the gram‐positive bacteria Staphylococcus. aureus. Polydopamine‐modified montmorillonite (PDA−Mt) was used to reduce silver ions into silver nanoparticles through the hydroxyl groups of polydopamine. The chemical properties and morphology of AgNP/PDA−Mt were analyzed by X‐ray diffraction spectroscopy (XRD), fourier transform infrared spectroscopy (FT‐IR), transmission electron microscope (TEM), scanning electron microscope (SEM), etc. Also, its antimicrobial property has been investigated. The results showed that AgNP/PDA−Mt possessed significant sterilization at low doses. And the results had been shown its acceptable biocompatibility.

Publisher

Wiley

Subject

General Chemistry

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