Biologically Active Quinoline‐Hydrazone Conjugates as Potential Trypanosoma cruzi DHFR‐TS Inhibitors: Docking, Molecular Dynamics, MM/PBSA and Drug‐Likeness Studies

Author:

Yepes Andrés F.1,Quintero‐Saumeth Jorge2,Cardona‐Galeano Wilson1

Affiliation:

1. Chemistry of Colombian Plants, Institute of Chemistry, Faculty of Exact and Natural Sciences University of Antioquia-UdeA, Calle 70 No. 52-21, A.A 1226 Medellín Colombia

2. University of Pamplona Faculty of Basic Sciences, Pamplona, Colombia, Km 1 Vía Bucaramanga Ciudad Universitaria Pamplona Colombia

Publisher

Wiley

Subject

General Chemistry

Reference56 articles.

1. World Health Organization. Neglected tropical diseases report to be found under http://www.who.int/neglected_diseases/diseases/en.html 2020

2. World Health Organization Chagas disease (American Trypanosomiasis) report to be found under http://www.who.int/news-room/fact-sheets/detail/chagasdisease-(american-trypanosomiasis).html 2020.

3. A New Era for Chagas Disease Drug Discovery?

4. Antimalarial drug discovery: efficacy models for compound screening

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