A Metal‐Free KO<sup><i>t</i></sup>Bu‐Mediated Protocol towards the Synthesis of Quinolines, Indenoquinolines and Acridines-Reference-Cited by-同舟云学术

A Metal‐Free KO^tBu‐Mediated Protocol towards the Synthesis of Quinolines, Indenoquinolines and Acridines

Published:2024-01-23 Issue:4 Volume:9 Page:
ISSN:2365-6549
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language:en
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Author:

Satya Kishore Pendyala¹,Gujjarappa Raghuram²^ORCID,Jagdishbhai Patel Mayur³,Polina Saibabu¹,Kishore Putta V. P. Rama¹,Singh Virender⁴,Malakar Chandi C.²^ORCID,Pralhad Pujar Prasad¹^ORCID

Affiliation:

1. Department of Chemistry CHRIST (Deemed to be University) Bangalore 560029 India

2. Department of Chemistry National Institute of Technology Manipur Langol, Imphal - 795004 Manipur India

3. Department of Chemistry Indian Institute of Technology Guwahati Guwahati 781 039 Assam India

4. Department of Chemistry Central University of Punjab Bathinda 151001 Punjab India

Abstract

AbstractAn expeditious strategy has been developed for the synthesis of diverse quinolines, indenoquinolines and acridines using KOtBu‐mediated reaction conditions. The designed process utilizes 2‐aminoaryl carbaldehydes/2‐aminoaryl ketones and methyl/methylene group containing ketones as readily available feedstock. The chemical transformation was affected at room temperature within a short duration of time to obtain diverse N‐heterocycles yields up to 92 %. The established process also exhibits considerable functional group tolerance with an operational simplicity.

Publisher

Wiley

Subject

General Chemistry

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