Nanocatalyzed Synthesis of Benzoxazoles

Abstract

AbstractNaturally, occurring as well as synthetic nitrogen and oxygen containing heterocyclic compounds like benzoxazoles and its derivatives have found to be playing a vital role in the Pharmaceutical, agriculture; polymer, material science and they also exhibits series of significant antimicrobial activities. In the last decade, an organic transformation has found abundant application of nanotechnology and nanoscience can aid design catalyst with excellent efficiency, selectivity and stability. Academics and industry have recently shown a lot of interest in the application of nanocatalysts, a field that is expanding significantly, to create sustainable and environmentally friendly processes for the synthesis of benzoxazole derivatives with multi‐component reactions (MCRs). Nanocatalyst reactions have advantages over conventional catalyst reactions because of the interaction of chemical reactants made possible by a high surface area ratio, simple purification, low catalyst loading, high atom economy, inexpensiveness, short reaction time, better yield, and recyclability of the nanocatalysts. In this review article, mainly focus is on the nanocatalysts fabrications, characterizations and their applications for the synthesis of benzoxazoles moiety during the last decennary (2011 to 2022).