Affiliation:
1. Department of Pharmaceutics Faculty of Pharmacy Zabol University of Medical Sciences Zabol Iran
2. Department of Basic Sciences Neyshabur University of Medical Sciences Neyshabur 9318614139 Iran
3. School of Pharmacy Shahid beheshti University of Medical Sciences Tehran Iran
4. Educational Development Center Kerman University of Medical Sciences Kerman Iran
Abstract
AbstractThis report presents the outcomes of exerting extracted Salvadora persica for synthesizing ZnO nanoparticles (ZnO−NP) and Mn‐doped ZnO nanorods (Mn−ZnO−NRs) through a viable and economical “green” route. The products characteristics were configured by the means of X‐ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy‐dispersive X‐ray (EDX) spectroscopy, UV‐visible spectroscopy (UV‐Vis) and Raman assessing technics. As the constructional evaluations approved the progress of well crystalline nano, the EDX analyses approved the doping of Mn, which interestingly succeeded in significantly altering the spherical framework of ZnO into a rod‐looking structure. The following steps involved the employment of MTT trial to assay the cytotoxic impacts of our sample towards breast (MCF‐7: Michigan Cancer Foundation‐7) cancer cell line, resulting in confirming the superior outcomes of Mn−ZnO−NRs than the solitary case of ZnO. The boosted functionality of the doped product may be attributable to the appearance of Mn into the lattice of ZnO. In addition, the evolved morphology of ZnO, obtained through the doping process, could have caused substantial developments in the cytotoxic operation of doped sample as well.
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2 articles.
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