Affiliation:
1. Department of Chemistry Graduate University of Advanced Technology Kerman Iran
2. Environment Department, Institute of Science and High Technology and Environmental Sciences Graduate University of Advanced Technology Kerman Iran Tel.
Abstract
AbstractWe describe a simple hydrothermal method for preparing a nanocomposite of reduced graphene oxide/Mn3O4 (rGO/Mn3O4), and its use in electrochemically detecting tramadol (TRA). The sensor was constructed by using a glassy carbon electrode modified with a rGO/Mn3O4 nanocomposite (rGO/Mn3O4/GCE) as an electro‐catalyst. The electrochemical properties of TRA at rGO/Mn3O4/GCE were studied using cyclic voltammetry (CV), chronoamperometry, and differential pulse voltammetry (DPV) in a phosphate buffer solution (PBS) with a pH of 8.0. The oxidation peak currents of TRA on rGO/Mn3O4/GCE increased compared to the bare GCE. This enhancement was attributed to the high surface area and excellent electron transfer performance of the rGO/Mn3O4 nanocomposite on the surface of the electrode. Under optimal conditions, the oxidation peak currents exhibited a linear increase with the concentration of TRA within the range of 0.5 to 700.0 μM, and a detection limit (LOD) of 0.16 μM was achieved. This study has shown that the rGO/Mn3O4/GCE can effectively be used to analyze TRA in real specimens.