Affiliation:
1. Department of Pharmacy University of Patras University Campus GR-265 04 Rio Achaia Greece
2. Hellenic Pasteur Institute 127 Vas. Sofias Ave. GR-115 21 Athens Greece
3. 24 Pentelis St. GR-175 64 Athens Greece
Abstract
AbstractThe Nitroso entity, in its long history, has seen diverse applications in Chemistry, Biology and Medicine. In numerous chemical reactions it has been considered mainly as an electrophile. Its less radiant side, that of a nucleophile, has attracted limited attention. Discernible cases of its nucleophilic character and its potential are highlighted herein.