Affiliation:
1. Department of Applied Chemistry Kyungpook National University 80 Daehakro, Bukgu Daegu 41566 Republic of Korea
Abstract
AbstractTreatment of 2‐(2‐bromoaryl)‐ and 2‐(2‐bromovinyl)benzimidazoles with cyclohexane‐1,3‐diones in DMF in the presence of reusable Fe3O4@SiO2@MOF‐199 along with L‐proline and Cs2CO3 afforded 2,3‐dihydrobenzo[4,5]imidazo[1,2‐f]phenanthridin‐4(1H)‐ones and 2,3‐dihydrobenzo[4,5]imidazo[1,2‐a]quinolin‐4(1H)‐ones, respectively, in moderate to good yields. Such C(sp2)−C coupled and cyclized scaffolds were aromatized to benzo[4,5]imidazo[1,2‐f]phenanthridines and benzo[4,5]imidazo[1,2‐a]quinolines in good yields by a one‐pot sequential treatment with NaBH4, POCl3/pyridine, and DDQ.