Affiliation:
1. School of Physical Sciences Jawaharlal Nehru University 110 067 New Delhi India
2. Department of Chemistry Guru Ghasidas Vishwavidyalaya Central University) 495 009 Bilaspur C.G. India
3. Department of Chemistry University of Lucknow 220 007 Lucknow U.P. India
Abstract
AbstractUnprecedented catalyst‐free synthesis of chromen‐4‐ones and bezothiophen‐3‐ones via insertion of in situ prepared benzyne intermediate into masked enal and masked mercapto acid is reported herein. The envisaged methodology does not need any catalyst and involves cycloaddition of benzyne, formed in situ, with 2,2,6‐trimethyl‐1,3‐dioxin‐4‐one and 2‐methyl‐2‐phenyl‐1,3‐oxathiolan‐5‐one to afford the target chromen‐4‐ones (75–89 %) and benzothiophen‐3‐ones (69–86 %) respectively.
Funder
Science and Engineering Research Board