Affiliation:
1. Department of Chemistry Annamalai University, Annamalai Nagar Tamil Nadu 608 002 India
Abstract
AbstractIn this study, we synthesised a series of novel 1, 3‐oxazepine and characterized by FT‐IR, 1HNMR and 13CNMR spectral studies. Docking studies are carried out for the synthesised compound using five different proteins (PDB Code: 1HNY, 1VMP, 3A4A, 6W63 and 7JRN) and it proved that all the synthesised compounds having better binding affinity in anti‐oxidant (3A4A) proteins. Based on the docking result all the newly synthesised compounds are screened their antioxidant activity. The compounds showed a good activity towards antioxidant activity compared with standard. Furthermore, the SwissADME online application is used to analyses the physiochemical and pharmacokinetic features of the compounds.
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2 articles.
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