Affiliation:
1. Organic and Medicinal Chemistry Division Indian Institute of Chemical Biology (CSIR-IICB) 4 Raja S. C. Mullick Road Kolkata 700032 India.
2. Academy of Scientific and Innovative Research (AcSIR) Ghaziabad 201002 India.
Abstract
AbstractAn environmentally benign, efficient, practically applicable and C(sp3)−H functionalization of primary amines for the synthesis of highly substituted oxazoles from easily available internal alkynes was developed. This synthesis is toxic chemicals, transition‐metal free as well as mild and regioselective. This one‐pot methodology with broad substrate scope unlocks a green avenue for the synthesis of highly functionalized oxazole derivatives with excellent yields.