Exploring Untouched Variant of Bis(2‐methyl‐1<i>H</i>‐indol‐3‐yl)methane: Enhances Chemo and Mono‐Selectivity-Reference-Cited by-同舟云学术

Exploring Untouched Variant of Bis(2‐methyl‐1H‐indol‐3‐yl)methane: Enhances Chemo and Mono‐Selectivity

Published:2024-06-18 Issue:23 Volume:9 Page:
ISSN:2365-6549
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language:en
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Author:

Merneedi Ravikumar¹²,Singh Mamata³⁴¹⁵^ORCID,Bharty Manoj Kumar⁶

Affiliation:

1. Department of Chemistry, School of Sciences GITAM University, Doddaballapur Bengaluru, Karnataka India

2. Department of Chemistry Solutions Aragen Life Sciences, Bommasandra Bengaluru, Karnataka India

3. Department of Medicine, Division of Infectious Diseases Mayo Clinic Jacksonville, Florida USA

4. Computational Biology Division Mayo Clinic Jacksonville, Florida USA

5. Small Molecule Research Laboratory Indus Trust Bangalore, Karnataka India

6. Department of Chemistry, Institute of Science Banaras Hindu University Varanasi, U.P. India

Abstract

AbstractThe new derivatives of bis(2‐methyl‐1H‐indol‐3‐yl)methane are synthesized by employing decanoic acid to boost aldehyde reactivity via electrophilic activation. The reactions entail combining 2‐methyl‐1H‐indole with various aromatic, aliphatic, and heterocyclic aldehydes at room temperature for 24 h. The newly synthesized compound 4‐(bis(2‐methyl‐1H‐indol‐3‐yl)methyl)‐3‐bromophenol f) has been characterized through 2D structure elucidation. Chemo selectivity and mono selectivity have been explored.

Publisher

Wiley

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