DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease-Reference-Cited by-同舟云学术

DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease

Published:2018-05-21 Issue:2 Volume:68 Page:496-514
ISSN:0270-9139
Container-title:Hepatology
language:en
Short-container-title:Hepatology

Author:

Chen Hanqing¹²,Shen Feng¹²³,Sherban Alex⁴,Nocon Allison⁴,Li Yu⁴⁵^ORCID,Wang Hua⁶,Xu Ming-Jiang⁶,Rui Xianliang⁴,Han Jinyan⁴,Jiang Bingbing⁴,Lee Donghwan¹²,Li Na¹²⁷,Keyhani-Nejad Farnaz¹²,Fan Jian-gao³,Liu Feng²,Kamat Amrita⁸,Musi Nicolas²⁸,Guarente Leonard⁹,Pacher Pal⁶,Gao Bin⁶,Zang Mengwei¹²⁸

Affiliation:

1. Department of Molecular Medicine; University of Texas Health San Antonio; San Antonio TX

2. Barshop Institute for Longevity and Aging Studies, Center for Healthy Aging; University of Texas Health San Antonio; San Antonio TX

3. Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; Shanghai China

4. Boston University School of Medicine; Boston MA

5. Shanghai Institutes for Biological Sciences; Chinese Academy of Sciences; Shanghai China

6. Laboratory of Liver Diseases, Laboratory of Cardiovascular Physiology and Tissue Injury, National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; Bethesda MD

7. Shanghai General Hospital; Shanghai Jiao Tong University School of Medicine; Shanghai China

8. Geriatric Research, Education and Clinical Center; South Texas Veterans Health Care System; San Antonio TX

9. Department of Biology, Paul F. Glenn Laboratory; Massachusetts Institute of Technology; Cambridge MA

Funder

National Institutes of Health

Distinguished Chair Endowment Fund from the Ewing Halsell Foundation at the University of Texas Health Science Center at San Antonio

Publisher

Wiley

Subject

Hepatology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/hep.29849/fullpdf

Reference28 articles.

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3. mTOR signaling in growth control and disease;Laplante;Cell,2012

4. Inhibition of mTORC1 by astrin and stress granules prevents apoptosis in cancer cells;Thedieck;Cell,2013

5. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival;Peterson;Cell,2009

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