Comparative hepatic transport of desglycylated and cyclic metabolites of rilmazafone in rats: Analysis by multiple indicator dilution method-Reference-Cited by-同舟云学术

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Comparative hepatic transport of desglycylated and cyclic metabolites of rilmazafone in rats: Analysis by multiple indicator dilution method

Published:1993-05 Issue:4 Volume:14 Page:279-290
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm. Drug Dispos.

Author:

Muranushi Noriyuki,Miyauchi Seiji,Suzuki Hiroshi,Sugiyama Yuichi,Hanano Manabu,Kinoshita Haruki,Oguma Takayoshi,Yamada Hideo

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference18 articles.

1. Detection and determination of active metabolites of 1-(2-o-chlorobenzoyl-4-chlorophenyl)-5-glycyl-aminomethyl-3-dimethylcarbamoyl-1H-1,2,4-triazole hydrochloride dihydrate, (450191-S), in rat tissues, using a radioreceptor assay for benzodiazepines

2. Uptake of 450191-S, a 1H-1,2,4-triazolyl benzophenone derivative, in the everted sac of rat small intestine: Role of intestinal aminopeptidases.

3. Intestinal activation of a new sleep inducer 450191-s, a 1h-1,2,4-triazolyl benzophenone derivative, in rats.

4. Pharmacology of a new sleep-inducer, 1H-1,2,4-triazolyl benzophenone derivative, 450191-S. (VIII). Examination and determination of metabolites in human plasma and urine.

5. Biopharmaceutical characterization of 450191-S, a ring-opened derivative of 1,4-benzodiazepine. I Active metabolite levels in rat plasma.

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1. Prodrug Strategies to Enhance Oral Drug Absorption;Oral Bioavailability;2011-07-05

2. Analysis Methods and Recent Advances in Nonlinear Pharmacokinetics from In Vitro through In Loci to In Vivo;Drug Metabolism and Pharmacokinetics;2004

3. Membrane transport in hepatic clearance of drugs .1. Extended hepatic clearance models incorporating concentration-dependent transport and elimination processes;Pharmaceutical Research;1997

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