Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: a report from the female lung cancer consortium in Asia

Author:

Machiela Mitchell J.1,Hsiung Chao Agnes2,Shu Xiao-Ou34,Seow Wei Jie1,Wang Zhaoming5,Matsuo Keitaro6,Hong Yun-Chul7,Seow Adeline8,Wu Chen910,Hosgood H. Dean11,Chen Kexin12,Wang Jiu-Cun1314,Wen Wanqing34,Cawthon Richard15,Chatterjee Nilanjan1,Hu Wei1,Caporaso Neil E.1,Park Jae Yong16,Chen Chien-Jen17,Kim Yeul Hong18,Kim Young Tae19,Landi Maria Teresa1,Shen Hongbing2021,Lawrence Charles22,Burdett Laurie5,Yeager Meredith5,Chang I-Shou23,Mitsudomi Tetsuya24,Kim Hee Nam25,Chang Gee-Chen2627,Bassig Bryan A.128,Tucker Margaret1,Wei Fusheng29,Yin Zhihua30,An She-Juan31,Qian Biyun32,Lee Victor Ho Fun33,Lu Daru13,Liu Jianjun3435,Jeon Hyo-Sung36,Hsiao Chin-Fu237,Sung Jae Sook38,Kim Jin Hee39,Gao Yu-Tang40,Tsai Ying-Huang41,Jung Yoo Jin19,Guo Huan42,Hu Zhibin2021,Hutchinson Amy5,Wang Wen-Chang2,Klein Robert J.43,Chung Charles C.1,Oh In-Jae4445,Chen Kuan-Yu46,Berndt Sonja I.1,Wu Wei30,Chang Jiang9,Zhang Xu-Chao31,Huang Ming-Shyan47,Zheng Hong12,Wang Junwen4849,Zhao Xueying13,Li Yuqing50,Choi Jin Eun51,Su Wu-Chou52,Park Kyong Hwa18,Sung Sook Whan53,Chen Yuh-Min5455,Liu Li56,Kang Chang Hyun19,Hu Lingmin2021,Chen Chung-Hsing23,Pao William57,Kim Young-Chul4445,Yang Tsung-Ying27,Xu Jun58,Guan Peng30,Tan Wen9,Su Jian31,Wang Chih-Liang59,Li Haixin12,Sihoe Alan Dart Loon60,Zhao Zhenhong13,Chen Ying8,Choi Yi Young51,Hung Jen-Yu47,Kim Jun Suk61,Yoon Ho-Il62,Cai Qiuyin34,Lin Chien-Chung52,Park In Kyu19,Xu Ping63,Dong Jing2021,Kim Christopher1,He Qincheng30,Perng Reury-Perng54,Kohno Takashi64,Kweon Sun-Seog6566,Chen Chih-Yi67,Vermeulen Roel C.H68,Wu Junjie13,Lim Wei-Yen8,Chen Kun-Chieh27,Chow Wong-Ho1,Ji Bu-Tian1,Chan John K. C.69,Chu Minjie2021,Li Yao-Jen17,Yokota Jun6470,Li Jihua71,Chen Hongyan13,Xiang Yong-Bing72,Yu Chong-Jen46,Kunitoh Hideo73,Wu Guoping29,Jin Li13,Lo Yen-Li2,Shiraishi Kouya64,Chen Ying-Hsiang2,Lin Hsien-Chih2,Wu Tangchun42,Wong Maria Pik74,Wu Yi-Long31,Yang Pan-Chyr75,Zhou Baosen30,Shin Min-Ho66,Fraumeni Joseph F.1,Zheng Wei34,Lin Dongxin9,Chanock Stephen J.1,Rothman Nathaniel1,Lan Qing1

Affiliation:

1. Division of Cancer Epidemiology and Genetics; National Cancer Institute; Bethesda MD

2. Institute of Population Health Sciences, National Health Research Institutes; Zhunan Taiwan

3. Department of Medicine; Vanderbilt University Medical Center; Nashville TN

4. Vanderbilt-Ingram Cancer Center; Vanderbilt University Medical Center; Nashville TN

5. Cancer Genomics Research Laboratory; Division of Cancer Epidemiology and Genetics; National Cancer Institute; Bethesda MD

6. Division of Epidemiology and Prevention; Aichi Cancer Center Research Institute; Nagoya Japan

7. Department of Preventive Medicine; Seoul National University College of Medicine; Seoul Republic of Korea

8. Saw Swee Hock School of Public Health; National University of Singapore; Republic of Singapore

9. Department of Etiology and Carcinogenesis; Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Beijing China

10. State Key Laboratory of Molecular Oncology; Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Beijing China

11. Department of Epidemiology and Population Health; Albert Einstein College of Medicine; Bronx NY

12. Department of Epidemiology and Biostatistics; Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Medical University Cancer Institute and Hospital; Tianjin China

13. Ministry of Education Key Laboratory of Contemporary Anthropology; School of Life Sciences; Fudan University; Shanghai China

14. State Key Laboratory of Genetic Engineering; School of Life Sciences; Fudan University; Shanghai China

15. Department of Human Genetics; University of Utah; Salt Lake City UT

16. Lung Cancer Center; Kyungpook National University Medical Center; Daegu Republic of Korea

17. Genomic Research Center; Taipei Taiwan

18. Department of Internal Medicine; Division of Oncology/Hematology; College of Medicine; Korea University Anam Hospital; Seoul Republic of Korea

19. Department of Thoracic and Cardiovascular Surgery; Cancer Research Institute, Seoul National University College of Medicine; Seoul Republic of Korea

20. Jiangsu Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University; Nanjing China

21. Jiangsu Key Laboratory of Cancer Biomarkers; Prevention and Treatment; Cancer Center; School of Public Health; Nanjing Medical University; Nanjing China

22. Westat; Rockville MD

23. National Institute of Cancer Research, National Health Research Institutes; Zhunan Taiwan

24. Division of Thoracic Surgery; Kinki University School of Medicine; Sayama Japan

25. Center for Creative Biomedical Scientists; Chonnam National University; Gwangju Republic of Korea

26. Department of Medicine; School of Medicine; National Yang-Ming University; Taipei Taiwan

27. Department of Internal Medicine; Division of Chest Medicine; Taichung Veterans General Hospital; Taichung Taiwan

28. Division of Environmental Health Sciences; Yale School of Public Health; New Haven CT

29. China National Environmental Monitoring Center; Beijing China

30. Department of Epidemiology; School of Public Health, China Medical University; Shenyang China

31. Guangdong Lung Cancer Institute, Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer, Guangdong General Hospital, Guangdong Academy of Medical Sciences; Guangzhou China

32. Department of Epidemiology and Biostatistics; School of Public Health; Shanghai Jiao Tong University; Shanghai China

33. Department of Clinical Oncology; Li Ka Shing Faculty of Medicine; the University of Hong Kong; Hong Kong China

34. Department of Human Genetics; Genome Institute of Singapore; Republic of Singapore

35. School of Life Sciences; Anhui Medical University; Hefei China

36. Molecular Diagnostics and Imaging Center; Kyungpook National University; Daegu Republic of Korea

37. Taiwan Lung Cancer Tissue/Specimen Information Resource Center; National Health Research Institutes; Zhunan Taiwan

38. Cancer Research Institute, Korea University; Seoul Republic of Korea

39. Department of Environmental Health; Graduate School of Public Health, Seoul National University; Seoul Republic of Korea

40. Department of Epidemiology; Shanghai Cancer Institute; Shanghai China

41. Department of Respiratory Thearpy; Chang Gung Memorial Hospital; Chiayi Taiwan

42. Institute of Occupational Medicine and Ministry of Education Key Lab for Environment and Health, School of Public Health, Huazhong University of Science and Technology; Wuhan China

43. Department of Genetics and Genomic Sciences; Icahn School of Medicine at Mount Sinai; Icahn Institute for Genomics and Multiscale Biology; New York NY

44. Lung and Esophageal Cancer Clinic; Chonnam National University Hwasun Hospital; Hwasun-Eup Republic of Korea

45. Department of Internal Medicine; Chonnam National University Medical School; Gwangju Republic of Korea

46. Department of Internal Medicine; National Taiwan University Hospital; Taipei Taiwan

47. Department of Internal Medicine; Kaohsiung Medical University Hospital, School of Medicine, Kaohsiung Medical University; Kaohsiung Taiwan

48. Centre for Genomic Sciences; Li Ka Shing Faculty of Medicine; the University of Hong Kong; Hong Kong China

49. Department of Biochemistry; Li Ka Shing Faculty of Medicine; the University of Hong Kong; Hong Kong China

50. Cancer Prevention Institute of California; Fremont CA

51. Cancer Research Center; Kyungpook National University Medical Center; Daegu Republic of Korea

52. Department of Internal Medicine; Cancer Center, National Cheng Kung University Hospital, National College of Medicine, Cheng Kung University; Tainan Taiwan

53. Department of Thoracic and Cardiovascular Surgery; Seoul St Mary's Hospital; Seoul Republic of Korea

54. Department of Chest Medicine; Taipei Veterans General Hospital; Taipei Taiwan

55. Taipei Cancer Center; Taipei Medical University; Taipei Taiwan

56. Cancer Center; Union Hospital, Huazhong University of Science and Technology; Wuhan China

57. Division of Hematology and Oncology; Vanderbilt University Medical Center; Nashville TN

58. School of Public Health; the University of Hong Kong; Hong Kong

59. Department of Pulmonary and Critical Care; Chang Gung Memorial Hospital; Taoyuan Taiwan

60. Department of Surgery; Division of Cardiothoracic Surgery; Queen Mary Hospital; Hong Kong China

61. Department of Internal Medicine; Division of Medical Oncology; College of Medicine, Korea University Guro Hospital; Seoul Republic of Korea

62. Department of Internal Medicine; Seoul National University Bundang Hospital; Seongnam Republic of Korea

63. Department of Oncology; Wuhan Iron and Steel Corporation Staff Worker Hospital; Wuhan China

64. Division of Genome Biology; National Cancer Center Research Institute; Tokyo Japan

65. Jeonnam Regional Cancer Center; Chonnam National University Hwasun Hospital; Hwasun-Eup Republic of Korea

66. Department of Preventive Medicine; Chonnam National University Medical School; Gwangju Republic of Korea

67. Institute of Medicine, Division of Thoracic Surgery, Department of Surgery, Chung Shan Medical University, Chung Shan Medical University Hospital; Taichung Taiwan

68. Division of Environmental Epidemiology; Institute for Risk Assessment Sciences (IRAS), Utrecht University; Utrecht The Netherlands

69. Department of Pathology; Queen Elizabeth Hospital; Hong Kong China

70. Institute of Predictive and Personalized Medicine of Cancer (IMPPC); Barcelona Spain

71. Qujing Center for Diseases Control and Prevention; Sanjiangdadao Qujing China

72. Department of Epidemiology; Shanghai Cancer Institute; Renji Hospital; School of Medicine; Shanghai Jiao Tong University; Shanghai China

73. Department of Medical Oncology; Japanese Red Cross Medical Center; Tokyo Japan

74. Department of Pathology; Li Ka Shing Faculty of Medicine; the University of Hong Kong; Hong Kong China

75. Department of Internal Medicine; National Taiwan University College of Medicine; Taipei Taiwan

Funder

National Cancer Institute

Ministry of Science and Technology of the People's Republic of China

Government of Jiangsu Province

National Natural Science Foundation of China

National Science Council Taiwan

U.S. Department of Health and Human Services

National Research Foundation of Korea

China Medical Board

Agency for Science, Technology and Research (A*STAR) of Singapore

China National High-Tech Research and Development Program

Chinese Lung Cancer Research Foundation

Foundation of Guangdong Science and Technology Department

General Research Fund of Research Grant Council, Hong Kong

Guangzhou Science and Information Technology Bureau

Jiangsu Higher Education Institution

Liaoning Provincial Department of Education

Ministry of Education, Science, Sports, Culture and Technology of Japan

Ministry of Health

Ministry of Health & Welfare, Republic of Korea

Ministry of Health, Labor, and Welfare for Research on Applying Health Technology

National Basic Research Program

National Cancer Center Research and Development Fund

National Foundation for Cancer Research

National Key Basic Research and Development Program

National Key Basic Research Program

National Medical Research Council Singapore

National Nature Science Foundation of China

National Research Program for Biopharmaceuticals in Taiwan

National Research Program on Genomic Medicine in Taiwan

National S&T Major Special Project

National Science Foundation of China

Natural Science Foundation of Guangdong Province

Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT)

Tianjin Cancer Institute and Hospital

Publisher

Wiley

Subject

Cancer Research,Oncology

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