Astragaloside IV alleviates oxidative stress‑related damage via inhibiting NLRP3 inflammasome in a MAPK signaling dependent pathway in human lens epithelial cells
Author:
Affiliation:
1. Department of Ophthalmology Hospital of Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China
Publisher
Wiley
Subject
Drug Discovery
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ddr.21929
Reference26 articles.
1. Acrylamide induces NLRP3 inflammasome activation via oxidative stress- and endoplasmic reticulum stress-mediated MAPK pathway in HepG2 cells
2. Eaf2 protects human lens epithelial cells against oxidative stress‑induced apoptosis by Wnt signaling
3. Icariside I specifically facilitates ATP or nigericin-induced NLRP3 inflammasome activation and causes idiosyncratic hepatotoxicity
4. Mitochondria and the permeability transition pore in cancer metabolic reprogramming
5. Astragaloside IV suppresses inflammatory response via suppression of NF-κB, and MAPK signalling in human bronchial epithelial cells
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1. MAPK Pathways in Ocular Pathophysiology: Potential Therapeutic Drugs and Challenges;Cells;2023-02-14
2. Astragaloside IV inhibits the proliferation and migration of lens epithelial cells induced by TGF-β through the Jagged-1/Notch pathway;Quality Assurance and Safety of Crops & Foods;2023-01-01
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