Characterization of dose-response for count data using a generalized MCP-Mod approach in an adaptive dose-ranging trial
Author:
Affiliation:
1. F. Hoffmann-La Roche Ltd., Clinical Pharmacology; Basel Switzerland
2. Novartis Pharma AG; Basel Switzerland
3. Novartis Pharmaceutical; East Hanover NJ USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology,Statistics and Probability
Reference25 articles.
1. USA Food and Drug Administration Challenge and opportunity on the critical path to new medical products USA Food and Drug Administration 2004
2. Practical considerations for optimal designs in clinical dose finding studies;Bretz;Statistics in Medicine,2010
3. Innovative approaches for designing and analyzing adaptive dose-ranging trials (with discussion);Bornkamp;Journal of Biopharmaceutical Statistics,2007
4. A case study of model-based Bayesian dose response estimation;Tan;Statistics in Medicine,2011
5. A Bayesian predictive strategy for an adaptive two-stage design in phase II clinical trials;Sambucini;Statistics in Medicine,2010
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