Dose intra‐subject escalation to an event ( DIETE ): A new method for phase 1 dose‐finding utilizing systematic intra‐subject dose escalation with application to T‐cell engagers-Reference-Cited by-同舟云学术

Dose intra‐subject escalation to an event ( DIETE ): A new method for phase 1 dose‐finding utilizing systematic intra‐subject dose escalation with application to T‐cell engagers

Published:2021-05-24 Issue:6 Volume:20 Page:1200-1215
ISSN:1539-1604
Container-title:Pharmaceutical Statistics
language:en
Short-container-title:Pharmaceutical Statistics

Author:

Xu Chenjia¹^ORCID,Zhuo Bin²,Rasmussen Hans Erik²^ORCID

Affiliation:

1. Richard M. Fairbanks School of Public Health Indiana University Indianapolis Indiana USA

2. Amgen Inc. Thousand Oaks California USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology,Statistics and Probability

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/pst.2140

Reference23 articles.

1. Redirected T Cell Cytotoxicity in Cancer Therapy

2. Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling

3. Blinatumomab for the treatment of acute lymphoblastic leukemia

4. A novel BCMA/CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo

5. Preclinical Characterization of AMG 330, a CD3/CD33-Bispecific T-Cell–Engaging Antibody with Potential for Treatment of Acute Myelogenous Leukemia

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