Downregulation of uPAR promotes urokinase translocation into the nucleus and epithelial to mesenchymal transition in neuroblastoma

Author:

Semina Ekaterina V.12ORCID,Rubina Kseniya A.13ORCID,Shmakova Anna A.12ORCID,Rysenkova Karina D.12ORCID,Klimovich Polina S.12ORCID,Aleksanrushkina Natalya A.1ORCID,Sysoeva Veronika Y.1ORCID,Karagyaur Maxim N.1ORCID,Tkachuk Vsevolod A.12ORCID

Affiliation:

1. Department of Biochemistry and Molecular Medicine, Faculty of MedicineLomonosov Moscow State University Moscow Russia

2. Laboratory of Molecular EndocrinologyInstitute of Experimental Cardiology, Federal State Budgetary Organization National Cardiology Research Center Ministry of Health of the Russian Federation Moscow Russia

3. Laboratory of Morohogenesis and Tissue Reparation, Faculty of MedicineLomonosov Moscow State University Moscow Russia

Funder

Russian Science Foundation

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Reference78 articles.

1. ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK);Aguirre‐Ghiso J. A.;Cancer Research,2003

2. Interleukin-6 in the Bone Marrow Microenvironment Promotes the Growth and Survival of Neuroblastoma Cells

3. EGF stimulates uPAR expression and cell invasiveness through ERK, AP‐1, and NF‐kappaB signaling in human gastric carcinoma cells;Baek M. K.;Oncology Reports,2008

4. A Quick & Automated Method for Measuring Cell Area Using ImageJ

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