Crystal structure of 6-guanidinohexanoyl trypsin near the optimum pH reveals the acyl-enzyme intermediate to be deacylated
Author:
Publisher
Wiley
Subject
Molecular Biology,Biochemistry,Structural Biology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/prot.24206/fullpdf
Reference19 articles.
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3. Structure of an acyl-enzyme intermediate during catalysis: (guanidinobenzoyl) trypsin;Mangel;Biochemistry,1990
4. Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates;Radisky;Proc Natl Acad Sci USA,2006
5. Molecular dynamics simulations of the acyl-enzyme and the tetrahedral intermediate in the deacylation step of serine proteases;Topf;Proteins,2002
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