Study of alteplase for respiratory failure in severe acute respiratory syndrome coronavirus 2/COVID‐19: Study design of the phase IIa STARS trial

Author:

Moore Hunter B.1,Barrett Christopher D.23ORCID,Moore Ernest E.14,Jhunjhunwala Rashi3,McIntyre Robert C.1,Moore Peter K5,Wang Janice6,Hajizadeh Negin6,Talmor Daniel S.7,Sauaia Angela18,Yaffe Michael B.23ORCID

Affiliation:

1. Department of Surgery School of Medicine University of Colorado Denver Aurora CO USA

2. Departments of Biological Engineering and Biology Koch Institute for Integrative Cancer Research Center for Precision Cancer Medicine Massachusetts Institute of Technology Cambridge MA USA

3. Division of Acute Care Surgery, Trauma and Surgical Critical Care Department of Surgery Beth Israel Deaconess Medical Center Harvard Medical School Boston MA USA

4. Department of Surgery Ernest E Moore Shock Trauma Center at Denver Health Denver CO USA

5. Department of Medicine School of Medicine University of Colorado Denver Denver CO USA

6. Feinstein Institutes for Medical Research Northwell Health Manhasset NY USA

7. Department of Anesthesia, Critical Care and Pain Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston MA USA

8. Colorado School of Public Health University of Colorado Denver Denver CO USA

Funder

Genentech

Publisher

Wiley

Subject

Hematology

Reference87 articles.

1. A pathological report of three COVID‐19 cases by minimally invasive autopsies;Yao XH;Zhonghua Bing Li Xue Za Zhi,2020

2. Clinical course and outcomes of critically ill patients with SARS‐CoV‐2 pneumonia in Wuhan, China: a single‐centered, retrospective, observational study. Lancet;Yang X;Respir Med,2020

3. Anticoagulant therapy for septic coagulopathy and disseminated intravascular coagulation: where do KyberSept and SCARLET leave us?

4. Clinical Characteristics of Coronavirus Disease 2019 in China

5. Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy

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