Synthesis, radiofluorination, and preliminary evaluation of the potential 5-HT2Areceptor agonists [18F]Cimbi-92 and [18F]Cimbi-150-Reference-Cited by-同舟云学术

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Synthesis, radiofluorination, and preliminary evaluation of the potential 5-HT2Areceptor agonists [18F]Cimbi-92 and [18F]Cimbi-150

Published:2017-09-18 Issue:12 Volume:60 Page:586-591
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J Label Compd Radiopharm

Author:

Edgar Fraser Graeme¹,Hansen Hanne D.²,Leth-Petersen Sebastian¹,Ettrup Anders²,Kristensen Jesper L.¹,Knudsen Gitte M.²³,Herth Matthias M.¹²⁴^ORCID

Affiliation:

1. Department of Drug Design and Pharmacology; University of Copenhagen; Copenhagen Denmark

2. Neurobiology Research Unit and Center for Integrated Molecular Brain Imaging; Copenhagen Denmark

3. University of Copenhagen; Copenhagen Denmark

4. Department of Clinical Physiology, Nuclear Medicine and PET; Copenhagen Denmark

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Reference39 articles.

1. Contribution of 5-HT2 receptor subtypes to sleep-wakefulness and respiratory control, and functional adaptations in knock-out mice lacking 5-HT2A receptors;Popa;J Neurosci,2005

2. Decreased frontal cortical serotonin(2A) receptors in schizophrenia;Dean;Schizophr Res,1996

3. Irving page lecture: 5-HT(2A) serotonin receptor biology: interacting proteins, kinases and paradoxical regulation;Roth;Neuropharmacology,2011

4. Mechanism of action of trazodone: a multifunctional drug;Stahl;CNS Spectr,2009

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1. Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors;Journal of Medicinal Chemistry;2022-08-08

2. 18F-AlF Labeled Peptide and Protein Conjugates as Positron Emission Tomography Imaging Pharmaceuticals;Bioconjugate Chemistry;2018-02-21

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