Exposure-Response Model of Subcutaneous C1-Inhibitor Concentrate to Estimate the Risk of Attacks in Patients With Hereditary Angioedema

Author:

Zhang Ying1,Tortorici Michael A.1ORCID,Pawaskar Dipti1,Pragst Ingo2,Machnig Thomas3,Hutmacher Matthew4,Zuraw Bruce5,Cicardi Marco6,Craig Timothy7,Longhurst Hilary8,Sidhu Jagdev9

Affiliation:

1. Clinical Pharmacology and Early Development; CSL Behring; King of Prussia Pennsylvania USA

2. Global Clinical Research, CSL Behring GmbH; Marburg Germany

3. Department of Global Clinical Development/Medical Affairs; CSL Behring GmbH; Marburg Germany

4. Deceased. Ann Arbor Pharmacometrics Group; Ann Arbor Michigan USA

5. Department of Medicine; University of California, San Diego; La Jolla California USA

6. Ospedale Luigi Sacco-UO Medicina Generale; Milan Italy

7. Department of Medicine; Pediatrics and Graduate Studies, Penn State University; Hershey Pennsylvania USA

8. Barts Health NHS Trust; London UK

9. Clinical Pharmacology and Early Development; CSL Limited; Parkville Australia

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Reference11 articles.

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