Translational Model to Predict Pulmonary Pharmacokinetics and Efficacy in Man for Inhaled Bronchodilators-Reference-Cited by-同舟云学术

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Translational Model to Predict Pulmonary Pharmacokinetics and Efficacy in Man for Inhaled Bronchodilators

Published:2017-12-27 Issue:3 Volume:7 Page:147-157
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacometrics Syst. Pharmacol.

Author:

Hendrickx Ramon¹,Lamm Bergström Eva¹,Janzén David L. I.²,Fridén Markus¹,Eriksson Ulf³,Grime Ken¹,Ferguson Douglas⁴

Affiliation:

1. DMPK, Respiratory, Inflammation, and Autoimmunity, IMED Biotech Unit, AstraZeneca; Gothenburg Sweden

2. DMPK, Cardiovascular and Metabolic Diseases, IMED Biotech Unit, AstraZeneca; Gothenburg Sweden

3. Early Clinical Development, IMED Biotech Unit, AstraZeneca; Gothenburg Sweden

4. DMPK, Oncology, IMED Biotech Unit, AstraZeneca; Boston Massachusetts USA

Publisher

Wiley

Subject

Pharmacology (medical),Modelling and Simulation

Reference34 articles.

1. Pharmacokinetic/pharmacodynamic evaluation of inhalation drugs: application to targeted pulmonary delivery systems;Tayab;Expert Opin. Drug Deliv.,2005

2. Pharmacometric models for characterizing the pharmacokinetics of orally inhaled drugs;Borghardt;AAPS J.,2015

3. Benchmarking of human dose prediction for inhaled medicines from preclinical in vivo data;Ericsson;Pharm. Res.,2017

4. Population pharmacodynamic model of the longitudinal FEV1 response to an inhaled long-acting anti-muscarinic in COPD patients;Wu;J. Pharmacokinet. Pharmacodyn.,2011

5. Longitudinal FEV1 dose-response model for inhaled PF-00610355 and salmeterol in patients with chronic obstructive pulmonary disease;Nielsen;J. Pharmacokinet. Pharmacodyn.,2012

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3. Liposomes or Extracellular Vesicles: A Comprehensive Comparison of Both Lipid Bilayer Vesicles for Pulmonary Drug Delivery;Polymers;2023-01-07

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