Determination of the enantiomers of flecainide and two major metabolites in man by gas chromatography/mass spectrometry using negative ion chemical ionization and stable isotope labelled internal standards-Reference-Cited by-同舟云学术

Determination of the enantiomers of flecainide and two major metabolites in man by gas chromatography/mass spectrometry using negative ion chemical ionization and stable isotope labelled internal standards

Published:1990-04 Issue:4 Volume:19 Page:256-266
ISSN:1052-9306
Container-title:Biological Mass Spectrometry
language:en
Short-container-title:Biol. Mass Spectrom.

Author:

Fischer C.,Schönberger F.,Meese C. O.,Eichelbaum M.

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Spectroscopy

Reference27 articles.

1. Presented in part at the 7th International Symposium on Mass Spectrometry in Life Sciences, 23-26 August, Ghent, Belgium (1988).

2. Pharmacokinetic and pharmacodynamic consequences of stereoselective drug metabolism in man

3. Quantitation of Flecainide Acetate, A New Antiarrhythmic Agent, in Biological Fluids by Gas Chromatography with Electron-Capture Detection

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1. Analysis of Flecainide and Two Metabolites in Biological Specimens by HPLC: Application to a Fatal Intoxication;Journal of Analytical Toxicology;2003-01-01

2. Variable disposition kinetics and electrocardiographic effects of flecainide during repeated dosing in humans: Contribution of genetic factors, dose-dependent clearance, and interaction with amiodarone;Clinical Pharmacology and Therapeutics;1994-03

3. Mass Spectrometry in Drug Disposition and Pharmacokinetics;Pharmacokinetics of Drugs;1994

4. Gas Chromatography/Mass Spectrometry Validation of High-Performance Liquid Chromatography Analysis of Flecainide Enantiomers in Serum;Therapeutic Drug Monitoring;1992-10

5. Application of the Empore Solid-Phase Extraction Membrane to the Isolation of Drugs from Blood;Therapeutic Drug Monitoring;1992-10