Organic anion transporters and PI3K–AKT–mTOR pathway mediate the synergistic anticancer effect of pemetrexed and rhein-Reference-Cited by-同舟云学术

Organic anion transporters and PI3K–AKT–mTOR pathway mediate the synergistic anticancer effect of pemetrexed and rhein

Published:2019-10-06 Issue:4 Volume:235 Page:3309-3319
ISSN:0021-9541
Container-title:Journal of Cellular Physiology
language:en
Short-container-title:J Cell Physiol

Author:

Bu Tianci¹²,Wang Changyuan¹³,Jin Huan¹,Meng Qiang¹³,Huo Xiaokui¹³,Sun Huijun¹³^ORCID,Sun Pengyuan¹,Wu Jingjing¹,Ma Xiaodong¹,Liu Zhihao¹³^ORCID,Liu Kexin¹³^ORCID

Affiliation:

1. Department of Clinical Pharmacology College of Pharmacy, Dalian Medical University Dalian China

2. The First People's Hospital of Zunyi The Third Affiliated Hospital of Zunyi Medical College Zunyi Guizhou China

3. Provincial Key Laboratory for Pharmacokinetics and Transport Liaoning, Dalian Medical University Dalian China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcp.29218

Reference51 articles.

1. Chemoradiation therapy in nonsmall cell lung cancer

2. RETRACTED: Down-regulation of lncRNA ADAMTS9-AS2 contributes to gastric cancer development via activation of PI3K/Akt pathway

3. The effect of a novel transition state inhibitor of methylthioadenosine phosphorylase on pemetrexed activity

4. Role of mitochondrial permeability transition in human hepatocellular carcinoma Hep-G2 cell death induced by rhein

5. Piperlongumine induces apoptosis and autophagy in human lung cancer cells through inhibition of PI3K/Akt/mTOR pathway

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