In vitro metabolism of exemestane by hepatic cytochrome P450s: impact of nonsynonymous polymorphisms on formation of the active metabolite 17β-dihydroexemestane-Reference-Cited by-同舟云学术

In vitro metabolism of exemestane by hepatic cytochrome P450s: impact of nonsynonymous polymorphisms on formation of the active metabolite 17β-dihydroexemestane

Published:2017-04-27 Issue:3 Volume:5 Page:e00314
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol Res Perspect

Author:

Peterson Amity¹^ORCID,Xia Zuping¹,Chen Gang¹,Lazarus Philip¹

Affiliation:

1. Department of Pharmaceutical Sciences; Washington State University; Spokane Washington

Funder

U.S. Public Health Service

National Institutes of Health

U.S. Department of Health and Human Services

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/prp2.314/fullpdf

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3. CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population;Allabi;Pharmacogenet Genomics,2005

4. Influence of SLCO1B1 and CYP2C8 gene polymorphisms on rosiglitazone pharmacokinetics in healthy volunteers;Aquilante;Hum Genomics,2008

5. Exemestane's 17-hydroxylated metabolite exerts biological effects as an androgen;Ariazi;Mol Cancer Ther,2007

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