What Amount of Weight Loss Can Entail Anorexia Nervosa or Atypical Anorexia Nervosa After Bariatric Surgery?

Author:

Hebebrand Johannes12ORCID,Antel Jochen12ORCID,Conceição Eva3ORCID,Matthews Abigail4ORCID,Hinney Anke256ORCID,Peters Triinu256ORCID

Affiliation:

1. Department of Child and Adolescent Psychiatry, Psychotherapy and Psychosomatics, University Hospital Essen (AöR) University of Duisburg‐Essen Essen Germany

2. Center for Translational Neuro‐ and Behavioral Sciences, University Hospital Essen University of Duisburg‐Essen Essen Germany

3. Faculty of Psychology and Education Sciences University of Porto Porto Portugal

4. Department of Psychiatry and Psychology Mayo Clinic Rochester Minnesota USA

5. Section of Molecular Genetics in Mental Disorders University Hospital Essen Essen Germany

6. Institute of Sex and Gender‐Sensitive Medicine University Hospital Essen Essen Germany

Abstract

ABSTRACTObjectivePost‐operative development of restrictive eating disorders can occur in patients after bariatric surgery. In children and adolescents with anorexia nervosa (AN) or atypical AN, premorbid body mass index (BMI) has recently been shown to predict total weight loss. We hypothesized that pre‐operative BMI similarly predicts weight loss and the development of a restrictive eating disorder in adult bariatric patients.MethodA PubMed search identified case studies/series of 29 adult females who developed AN or atypical AN/eating disorder not otherwise specified following bariatric surgery. Non‐parametric Spearman's correlation (rs) between pre‐operative BMI and total weight loss was calculated; a scatterplot was used to illustrate the relationship between pre‐operative/premorbid BMI and weight loss in kg for 29 bariatric patients and 460 children and adolescents with AN or atypical AN as published previously.ResultsThe correlation between pre‐operative BMI and weight loss among bariatric patients was rs = 0.65 (p = 0.0001). Scatterplot data of this relationship fit the previously identified pattern in children and adolescents with AN or atypical AN.DiscussionThe prediction of weight loss by pre‐operative/premorbid BMI appears applicable across the weight spectrum, from underweight to severe obesity, thus strengthening our hypothesis of underlying regulatory mechanisms for the development of AN and atypical AN. Such data may guide the determination of critical weight loss thresholds that trigger eating disorder development in predisposed individuals.

Publisher

Wiley

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