Simplifying the clinical classification of polymerase gamma (POLG) disease based on age of onset; studies using a cohort of 155 cases

Author:

Hikmat Omar12,Naess Karin34,Engvall Martin35,Klingenberg Claus67,Rasmussen Magnhild89,Tallaksen Chantal ME1011,Brodtkorb Eylert1213,Ostergaard Elsebet14,Coo I. F. M1516,Pias‐Peleteiro Leticia17,Isohanni Pirjo1819,Uusimaa Johanna202122,Darin Niklas23,Rahman Shamima2425,Bindoff Laurence A.226ORCID

Affiliation:

1. Department of Pediatrics Haukeland University Hospital Bergen Norway

2. Department of Clinical Medicine (K1) University of Bergen Bergen Norway

3. Centre for Inherited Metabolic Diseases Karolinska University Hospital Stockholm Sweden

4. Department of Medical Biochemistry and Biophysics Karolinska Institutet Stockholm Sweden

5. Department of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden

6. Department of Paediatric and Adolescent Medicine University Hospital of North Norway Tromso Norway

7. Paediatric Research Group, Department of Clinical Medicine UiT ‐ The Arctic University of Norway Tromso Norway

8. Women and Children's Division, Department of Clinical Neurosciences for Children Oslo University Hospital Oslo Norway

9. Unit for Congenital and Hereditary Neuromuscular Disorders, Department of Neurology Oslo University Hospital Oslo Norway

10. Department of Neurology Oslo University Hospital Oslo Norway

11. Faculty of Medicine Institute of Clinical Medicine, University of Oslo Oslo Norway

12. Department of Neuroscience Norwegian University of Science and Technology Trondheim Norway

13. Department of Neurology and Clinical Neurophysiology St. Olav's University Hospital Trondheim Norway

14. Department of Clinical Genetics Copenhagen University Hospital Rigshospitalet Copenhagen Denmark

15. Department of Neurology Medical Spectrum Twente Enschede The Netherlands

16. Department of Genetics and Cell Biology University of Maastricht Maastricht The Netherlands

17. Department of Neurology Sant Joan de Déu Children's Hospital Barcelona Spain

18. Department of Pediatric Neurology Children's Hospital and Pediatric Research Center, University of Helsinki and Helsinki University Hospital Helsinki Finland

19. Stem Cells and Metabolism Research Program, Faculty of Medicine University of Helsinki Helsinki Finland

20. PEDEGO Research Unit University of Oulu Oulu Finland

21. Biocenter Oulu University of Oulu Oulu Finland

22. Department of Pediatric Neurology Clinic for Children and Adolescents, Medical Research Center, Oulu University Hospital Oulu Finland

23. Department of Pediatrics The Queen Silvia Children's Hospital, University of Gothenburg Gothenburg Sweden

24. Mitochondrial Research Group UCL Great Ormond Street Institute of Child Health London UK

25. Metabolic Unit Great Ormond Street Hospital for Children NHS Foundation Trust London UK

26. Department of Neurology Haukeland University Hospital Bergen Norway

Funder

Helse Vest

Publisher

Wiley

Subject

Genetics(clinical),Genetics

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