Molecular dynamics study of HIV-1 RT-DNA-nevirapine complexes explains NNRTI inhibition and resistance by connection mutations
Author:
Affiliation:
1. Center for Advanced Biotechnology and Medicine; Rutgers University; Piscataway New Jersey 08854
2. Department of Chemistry and Chemical Biology; Rutgers University; Piscataway New Jersey 08854
Publisher
Wiley
Subject
Molecular Biology,Biochemistry,Structural Biology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/prot.24460/fullpdf
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4. Elucidating the inhibition mechanism of HIV-1 non-nucleoside reverse transcriptase inhibitors through multicopy molecular dynamics simulations;Ivetac;J Mol Biol,2009
5. Thumbs down for HIV: domain level rearrangements do occur in the NNRTI-bound HIV-1 reverse transcriptase;Wright;J Am Chem Soc,2012
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