Affiliation:
1. Department of Cell and Developmental Biology University of Illinois at Urbana‐Champaign Champaign Illinois USA
2. Department of Comparative Biosciences University of Illinois at Urbana‐Champaign Champaign Illinois USA
Abstract
AbstractSpecification of the germline and its segregation from the soma mark one of the most crucial events in the lifetime of an organism. In different organisms, this specification can occur through either inheritance or inductive mechanisms. In species such as Xenopus and zebrafish, the specification of primordial germ cells relies on the inheritance of maternal germline determinants that are synthesized and sequestered in the germ plasm during oogenesis. In this review, we discuss the formation of the germ plasm, how germline determinants are recruited into the germ plasm during oogenesis, and the dynamics of the germ plasm during oogenesis and early embryonic development.
Funder
National Institutes of Health
Subject
Cell Biology,Developmental Biology,Genetics
Cited by
1 articles.
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