Application of Metathesis Protocols to the Stereocontrolled Synthesis of some Functionalized β‐Amino Esters and Azaheterocycles-Reference-Cited by-同舟云学术

Application of Metathesis Protocols to the Stereocontrolled Synthesis of some Functionalized β‐Amino Esters and Azaheterocycles

Published:2023-09-27 Issue:12 Volume:23 Page:
ISSN:1527-8999
Container-title:The Chemical Record
language:en
Short-container-title:The Chemical Record

Author:

Semghouli Anas¹,Nonn Melinda²,Remete Attila M.³,Fustero Santos⁴,Kiss Loránd¹^ORCID

Affiliation:

1. Institute of Organic Chemistry Stereochemistry Research Group Research Centre for Natural Sciences, H- 1117 Budapest Magyar tudósok krt. 2 Hungary

2. MTA TTK Lendület Artificial Transporter Research Group Institute of Materials and Environmental Chemistry Research Centre for Natural Sciences, H- 1117 Budapest Magyar tudósok krt. 2 Hungary

3. Institute of Pharmaceutical Chemistry University of Szeged, H- 6720 Szeged Eötvös u. 6 Hungary

4. Department of Organic Chemistry University of Valencia Pharmacy Faculty 46100- Burjassot Valencia Spain

Abstract

AbstractIn this account our aim was to give an insight into the application of metathesis protocols (ROM, RCM, RCEYM, CM, RRM) for the synthesis of various azaheterocyclic frameworks. Due to the high biological potential and importance in peptide chemistry and drug design of β‐amino acids our intention is to give a highlight on the synthetic procedures and transformation of these class of compounds with the above‐mentioned metathesis strategies with emphasis on selectivity, stereocontrol, substrate‐directing effect or functional group tolerance.

Funder

European Commission

Publisher

Wiley

Subject

Materials Chemistry,General Chemical Engineering,Biochemistry,General Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/tcr.202300279

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