Structural characterization ofin vitrorat liver microsomal metabolites of antihistamine desloratadine using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange HR-LC/MS

Author:

Chen Guodong,Daaro Ibrahim,Pramanik Birendra N.,Piwinski John J.

Publisher

Wiley

Subject

Spectroscopy

Reference44 articles.

1. Utility of mass spectrometry for pharmaceutical profiling applications;Kerns;Current Drug Metabolism,2006

2. Metabolite identification in drug discovery;Watt;Current Opinion in Drug Discovery and Development,2003

3. Minimizing the potential for metabolic activation in drug discovery;Kalgutkar;Expert Opinion on Drug Metabolism and Toxicology,2005

4. Detecting and characterizing reactive metabolites by liquid chromatography/tandem mass spectrometry;Ma;Journal of Mass Spectrometry,2006

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