New prediction categories in <scp>CASP15</scp>-Reference-Cited by-同舟云学术

New prediction categories in CASP15

Published:2023-06-12 Issue:12 Volume:91 Page:1550-1557
ISSN:0887-3585
Container-title:Proteins: Structure, Function, and Bioinformatics
language:en
Short-container-title:Proteins

Author:

Kryshtafovych Andriy¹^ORCID,Antczak Maciej²³,Szachniuk Marta²³^ORCID,Zok Tomasz²³,Kretsch Rachael C.⁴^ORCID,Rangan Ramya⁴,Pham Phillip⁵,Das Rhiju⁵⁶^ORCID,Robin Xavier⁷⁸^ORCID,Studer Gabriel⁷⁸^ORCID,Durairaj Janani⁷⁸,Eberhardt Jerome⁷⁸,Sweeney Aaron⁹,Topf Maya⁹¹⁰,Schwede Torsten⁷⁸^ORCID,Fidelis Krzysztof¹^ORCID,Moult John¹¹

Affiliation:

1. Genome Center University of California Davis California USA

2. Institute of Computing Science, Poznan University of Technology Poznan Poland

3. Institute of Bioorganic Chemistry, Polish Academy of Sciences Poznan Poland

4. Biophysics Program, Stanford University School of Medicine Stanford California USA

5. Biochemistry Department Stanford University School of Medicine Stanford California USA

6. Howard Hughes Medical Institute, Stanford University Stanford California USA

7. Biozentrum, University of Basel Basel Switzerland

8. SIB Swiss Institute of Bioinformatics Basel Switzerland

9. Centre for Structural Systems Biology (CSSB), Leibniz‐Institut für Virologie (LIV) Hamburg Germany

10. Universitätsklinikum Hamburg Eppendorf (UKE) Hamburg Germany

11. Institute for Bioscience and Biotechnology Research, Department of Cell Biology and Molecular genetics, University of Maryland Rockville Maryland USA

Abstract

AbstractPrediction categories in the Critical Assessment of Structure Prediction (CASP) experiments change with the need to address specific problems in structure modeling. In CASP15, four new prediction categories were introduced: RNA structure, ligand‐protein complexes, accuracy of oligomeric structures and their interfaces, and ensembles of alternative conformations. This paper lists technical specifications for these categories and describes their integration in the CASP data management system.

Funder

Howard Hughes Medical Institute

National Institutes of Health

Wellcome Trust

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prot.26515

Reference52 articles.

1. A large-scale experiment to assess protein structure prediction methods