Structural basis for binding of the renal carcinoma target hypoxia‐inducible factor 2α to prolyl hydroxylase domain 2
Author:
Affiliation:
1. Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford Oxford UK
2. Institute of Natural Medicine, University of Toyama Toyama Japan
Abstract
Funder
Wellcome Trust
Biotechnology and Biological Sciences Research Council
Cancer Research UK
Diamond Light Source
Publisher
Wiley
Subject
Molecular Biology,Biochemistry,Structural Biology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/prot.26541
Reference72 articles.
1. Hypoxia-inducible factor 1: master regulator of O2 homeostasis
2. Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
3. Oxygen sensing by HIF hydroxylases
4. The human oxygen sensing machinery and its manipulation
5. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
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