Impact of state legislation and institutional protocols on opioid prescribing practices following pediatric tonsillectomy

Author:

Einhorn Lisa M.1ORCID,Zhao Congwen2,Goldstein Benjamin A.23,Raman Sudha R.3,Cheng Jeffrey4ORCID

Affiliation:

1. Division of Pediatric Anesthesiology, Department of Anesthesiology Duke University Medical Center Durham North Carolina USA

2. Department of Biostatistics and Bioinformatics Duke University Medical Center Durham North Carolina USA

3. Department of Population Health Sciences Duke University School of Medicine Durham North Carolina USA

4. Division of Pediatric Otolaryngology, Department of Otolaryngology – Head and Neck Surgery and Communication Sciences Duke University Medical Center Durham North Carolina USA

Abstract

AbstractObjectivesTonsillectomy is a common pediatric surgery, and pain is an important consideration in recovery. Due to the opioid epidemic, individual states, medical societies, and institutions have all taken steps to limit postoperative opioids, yet few studies have examined the effect of these interventions on pediatric otolaryngology practices. The primary aim of this study was to characterize opioid prescribing practices following North Carolina state opioid legislation and targeted institutional changes.MethodsThis single center retrospective cohort study included 1552 pediatric tonsillectomy patient records from 2014 to 2021. The primary outcome was number of oxycodone doses per prescription. This outcome was assessed over three time periods: (1) Before 2018 North Carolina opioid legislation. (2) Following legislation, before institutional changes. (3) After institutional opioid‐specific protocols.ResultsThe mean (± standard deviation) number of doses per prescription in Periods 1, 2, and 3 was: 58 ± 53, range 4–493; 28 ± 36, range 3–488; and 23 ± 17, range 1–139, respectively. In the adjusted model, Periods 2 and 3 had lower doses by −41% (95% CI −49%, −32%) and −40% (95% CI −55%, −19%) compared to Period 1. After 2018 North Carolina legislation, dosage decreased by −9% (95% CI −13%, −5%) per year. Despite interventions, ongoing variability in prescription regimens remained in all periods.ConclusionLegislative and institution specific opioid interventions was associated with a 40% decrease in oxycodone doses per prescription following pediatric tonsillectomy. While variability in opioid practices decreased post‐interventions, it was not eliminated.Level of evidence3

Funder

National Center for Advancing Translational Sciences

National Institute of General Medical Sciences

Publisher

Wiley

Subject

General Medicine

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