Use of hydrogen/deuterium exchange mass spectrometry and mutagenesis as a tool to identify the binding region of inhibitors targeting the human mitotic kinesin Eg5-Reference-Cited by-同舟云学术

Use of hydrogen/deuterium exchange mass spectrometry and mutagenesis as a tool to identify the binding region of inhibitors targeting the human mitotic kinesin Eg5

Published:2006 Issue:3 Volume:20 Page:456-462
ISSN:0951-4198
Container-title:Rapid Communications in Mass Spectrometry
language:en
Short-container-title:Rapid Commun. Mass Spectrom.

Author:

Brier Sébastien,Lemaire David,DeBonis Salvatore,Kozielski Frank,Forest Eric

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference39 articles.

1. Hydrogen exchange and structural dynamics of proteins and nucleic acids

2. Probing the Non-covalent Structure of Proteins by Amide Hydrogen Exchange and Mass Spectrometry

3. Peer Reviewed: Investigating Protein Structure and Dynamics by Hydrogen Exchange MS

4. Hydrogen exchange methods to study protein folding

5. Folding of a four-helix bundle: studies of acyl-coenzyme A binding protein

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