P16INK4Aimmunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias

Author:

Mooren Jeroen J.1,Gültekin Sibel E.2,Straetmans Jos M.J.A.A.1,Haesevoets Annick3,Peutz-Kootstra Carine J.4,Huebbers Christian U.5,Dienes Hans P.6,Wieland Ulrike7,Ramaekers Frans C.S.3,Kremer Bernd1,Speel Ernst-Jan M.4,Klussmann Jens P.8

Affiliation:

1. Department of Otorhinolaryngology, Head and Neck Surgery, GROW-School for Oncology and Developmental Biology; Maastricht University Medical Centre; The Netherlands

2. Department of Oral Pathology, Faculty of Dentistry; Gazi University; Ankara Turkey

3. Department of Molecular Cell Biology, GROW-School for Oncology and Developmental Biology; Maastricht University Medical Centre; The Netherlands

4. Department of Pathology, GROW-School for Oncology and Developmental Biology; Maastricht University Medical Centre; The Netherlands

5. Jean-Uhrmacher-Institute for Otorhinolaryngological Research; University of Cologne; Germany

6. Department of Pathology; University of Cologne; Germany

7. Institute for Virology, University of Cologne; Germany

8. Department of Otorhinolaryngology, Head and Neck Surgery; University of Giessen; Germany

Funder

Dutch Cancer Foundation

Medical Research Foundation, Maastricht University Medical Centre

Publisher

Wiley

Subject

Cancer Research,Oncology

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