Ibrutinib Dosing Strategies Based on Interaction Potential of CYP3A4 Perpetrators Using Physiologically Based Pharmacokinetic Modeling
Author:
Affiliation:
1. Janssen Research & Development; Beerse Belgium
2. Janssen Research & Development; San Diego California USA
3. Pharmacyclics, Inc; Sunnyvale California USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Reference50 articles.
1. IMBRUVICA Prescribing Information http://www.imbruvica.com/ 2015
2. Physiologically-based pharmacokinetic modelling 2: predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions;Rodgers;J. Pharm. Sci.,2006
3. Absorption, metabolism, and excretion of oral (1)(4)C radiolabeled ibrutinib: an open-label, phase I, single-dose study in healthy men;Scheers;Drug Metab. Dispos.,2015
4. Stable isotope-intravenous microdose for absolute bioavailability and effect of grapefruit juice on ibrutinib in healthy adults;Vries;Br. J. Clin. Pharmacol.,2015
5. Effect of CYP3A perpetrators on ibrutinib exposure in healthy participants;Jong;Pharmacol. Res. Perspect.,2015
Cited by 91 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Evidence-based expert consensus on clinical management of safety of Bruton's tyrosine kinase inhibitors (2024);CHINESE J CANCER RES;2024
2. Chronic Lymphocytic Leukemia: Management of Adverse Events in the Era of Targeted Agents;Cancers;2024-05-24
3. Prevention and management of infectious complications in patients with chronic lymphocytic leukemia (CLL) treated with BTK and BCL-2 inhibitors, focus on current guidelines;Blood Reviews;2024-05
4. Bruton’s tyrosine kinase (BTK) inhibitors for the treatment of primary central nervous system lymphoma (PCNSL): current progress and latest advances;Leukemia & Lymphoma;2024-04-10
5. Regulatory Requirements and Applications of Physiologically Based Pharmacokinetic Models;ADME Processes in Pharmaceutical Sciences;2024
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3