Discordant prognosis of mismatch repair deficiency in colorectal and endometrial cancer reflects variation in antitumour immune response and immune escape

Author:

Glaire Mark A1,Ryan Neil AJ234,Ijsselsteijn Marieke E5ORCID,Kedzierska Katarzyna1,Obolenski Sofia1,Ali Reem1,Crosbie Emma J26ORCID,Bosse Tjalling5ORCID,Miranda Noel FCC5,Church David N178ORCID

Affiliation:

1. Cancer Genomics and Immunology Group, Wellcome Centre for Human Genetics University of Oxford Oxford UK

2. Division of Cancer Sciences, Faculty of Biology, Medicine and Health University of Manchester, St Mary's Hospital Manchester UK

3. Division of Evolution and Genomic Medicine, Faculty of Biology, Medicine and Health University of Manchester, St. Mary's Hospital Manchester UK

4. The Academic Women's Health Unit, Translational Health Sciences Bristol Medical School, University of Bristol Bristol UK

5. Department of Pathology Leiden University Medical Center Leiden The Netherlands

6. Department of Obstetrics and Gynaecology St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre Manchester UK

7. Oxford Cancer Centre, Churchill Hospital, Oxford University Hospitals Foundation NHS Trust Oxford UK

8. Oxford NIHR Comprehensive Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust Oxford UK

Funder

Cancer Research UK

European Commission

Horizon 2020 Framework Programme

KWF Kankerbestrijding

Medical Research Council Canada

National Institute for Health Research

Wellcome Trust

ZonMw

Publisher

Wiley

Subject

Pathology and Forensic Medicine

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