Cerebral and lung effects of a new generation synthetic surfactant with SP-B and SP-C analogs in preterm lambs

Author:

Rey-Santano Carmen1,Mielgo Victoria E.1,Murgia Xabier1,Gomez-Solaetxe Miguel Angel2,Salomone Fabrizio3,Bianco Federico3,Pelizzi Nicola3,Loureiro Begoña4,López de Heredia y Goya Jon4

Affiliation:

1. Animal Research Unit; BioCruces Health Research Institute; Barakaldo Bizkaia Spain

2. Medical Devices Group; University of Basque Country; Portugalete Bizkaia Spain

3. Chiesi Farmaceutici; R&D Department; Parma Italy

4. Neonatal Intensive Care Unit; Cruces University Hospital; Barakaldo Bizkaia Spain

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine,Pediatrics, Perinatology, and Child Health

Reference37 articles.

1. Microaerosol administration of synthetic β-g-Dipalmitoyl-L-α-Lecithin in the respiratory distress syndrome: a preliminar report;Robillard;Canad Med Ass J,1964

2. Synthetic surfactant based on analogues of SP-B and SP-C is superior to single-peptide surfactants in ventilated premature rabbits;Almlén;Neonatology,2010

3. Animal derived surfactant extract versus protein free synthetic surfactant for the prevention and treatment of respiratory distress syndrome;Ardell;Cochrane Database Syst Rev,2015

4. SP-B and SP-C containing new synthetic surfactant for treatment of extremely immature lamb lung;Sato;PLoS ONE,2012

5. New surfactant with SP-B and C analogs gives survival benefit after inactivation in preterm lambs;Seehase;PLoS ONE,2012

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