Substrate elasticity induces quiescence and promotes neurogenesis of primary neural stem cells—A biophysical in vitro model of the physiological cerebral milieu

Author:

Blaschke Stefan12,Vay Sabine Ulrike1,Pallast Niklas1,Rabenstein Monika1,Abraham Jella‐Andrea3,Linnartz Christina3,Hoffmann Marco3,Hersch Nils3,Merkel Rudolf3,Hoffmann Bernd3,Fink Gereon Rudolf12,Rueger Maria Adele12ORCID

Affiliation:

1. Department of NeurologyUniversity Hospital Cologne Cologne Germany

2. Cognitive NeuroscienceInstitute of Neuroscience and Medicine (INM‐3) Juelich Germany

3. Biomechanics SectionInstitute of Complex Systems (ICS‐7) Juelich Germany

Funder

'Gerok Program’ / Faculty of Medicine, University of Cologne, Germany

'Koeln Fortune Program` / Faculty of Medicine, University of Cologne, Germany

Marga-und-Walter-Boll-Stiftung

Publisher

Wiley

Subject

Biomedical Engineering,Biomaterials,Medicine (miscellaneous)

Reference61 articles.

1. Neurogenesis in adult subventricular zone;Alvarez‐Buylla A.;The Journal of Neuroscience,2002

2. Identification of neural stem cells in the adult vertebrate brain;Alvarez‐Buylla A.;Brain Research Bulletin,2002

3. The cyclin‐dependent kinase inhibitor p27 kip1 regulates radial stem cell quiescence and neurogenesis in the adult hippocampus;Andreu Z.;Stem Cells,2015

4. Generating neurons from stem cells;Androutsellis‐Theotokis A.;Methods in Molecular Biology,2008

5. Extracellular matrix: Functions in the nervous system;Barros C. S.;Cold Spring Harbor Perspectives in Biology,2011

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