Affiliation:
1. International Joint Research Laboratory for Biointerface and Biodetection Jiangnan University Wuxi Jiangsu 214122 P. R. China
2. State Key Laboratory of Food Science and Technology Jiangnan University Wuxi Jiangsu 214122 P. R. China
3. Department of Neurosurgery Jiangnan University Medical Center Wuxi Jiangsu 214002 P. R. China
4. The Key Laboratory of Carbohydrate Chemistry & Biotechnology Ministry of Education School of Biotechnology Jiangnan University Wuxi Jiangsu 214122 P. R. China
Abstract
AbstractChirality is a fundamental characteristic of living organisms and is commonly observed at the biomolecule, cellular, and tissue levels. Chiral nanomaterials play an irreplaceable role in nanomedicine and nanobiology because of their unique enantioselectivity with biological components. Here, research progress relating to chiral nanomaterials in the field of vaccines is reviewed, including antigen presenting systems, immune adjuvants, and cancer vaccines. First, the common synthesis methods are outlined for different types of chiral nanomaterials, as well as their chiral sources, optical properties, and potential biological applications. Then, the application of chiral nanomaterials are discussed in the field of vaccines with reference to the promotion of antigen presentation and activation of the immune system for tumor immunotherapy. Finally, the current obstacles and future research directions of chiral nanomaterials are revealed with regard to regulating the immune system.
Funder
National Outstanding Youth Science Fund Project of National Natural Science Foundation of China
National Natural Science Foundation of China
Subject
General Materials Science,General Chemistry
Cited by
4 articles.
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