CYTE-I-HD: Phase I dose finding and tolerability study of cysteamine (Cystagon) in Huntington's disease
Author:
Funder
Research Institute of the University of Kansas Medical Center
Publisher
Wiley
Subject
Neurology (clinical),Neurology
Reference22 articles.
1. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes;Huntington's Disease Collaborative Research Group;Cell,1993
2. Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract;Goldberg;Nat Genet,1996
3. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation;Davies;Cell,1997
4. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain;DiFiglia;Science,1997
5. Human genetic diseases due to codon reiteration: relationship to an evolutionary mechanism;Green;Cell,1993
Cited by 67 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Advances in Clinical Therapies for Huntington's Disease and the Promise of Multi‐Targeted/Functional Drugs Based on Clinicaltrials.gov;Clinical Pharmacology & Therapeutics;2024-06-11
2. Pathogenetic Contributions and Therapeutic Implications of Transglutaminase 2 in Neurodegenerative Diseases;International Journal of Molecular Sciences;2024-02-17
3. Mesenchymal Stem Cell Therapy for Huntington Disease: A Meta-Analysis;Stem Cells International;2023-04-30
4. Advances of H2S in Regulating Neurodegenerative Diseases by Preserving Mitochondria Function;Antioxidants;2023-03-06
5. Cysteamine hydrochloride, a transglutaminase2 inhibitor as therapeutic potential for oral submucous fibrosis;Journal of Indian Academy of Oral Medicine and Radiology;2023
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3