Evaluation of 6-Deoxy-amino-sugars as Potent Glycosidase Inhibitors. Importance of the CH2 OH(6) Group for Enzyme-Substrate Interaction
Author:
Affiliation:
1. Université de Haute-Alsace; Institut de Chimie J.-B. Donnet; 3bis rue Alfred Werner. F- 68093 Mulhouse Cedex France
2. Getima MSA
3. Novartis; Centre de Biotechnologie; 10 rue de l'Industrie, F- 68330 Huningue
Publisher
Wiley
Subject
General Chemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/slct.201601961/fullpdf
Reference60 articles.
1. Iminosugars: from botanical curiosities to licensed drugs
2. Sugar-mimic glycosidase inhibitors: natural occurrence, biological activity and prospects for therapeutic application
3. Polyhydroxylated alkaloids — natural occurrence and therapeutic applications
4. From Lianas to Glycobiology Tools: Twenty-Five Years of 2,5-Dideoxy-2,5-imino-D-mannitol
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