Exploring Quinazolinones as Anticonvulsants by Molecular Fragmentation Approach: Structural Optimization, Synthesis and Pharmacological Evaluation Studies

Author:

Ugale Vinod G.1ORCID,Bari Sanjay B.2,Khadse Saurabh C.1,Reddy Pedavenkatagari Narayana3,Bonde Chandrakant G.4,Chaudhari Prashant J.1

Affiliation:

1. Department of Pharmaceutical ChemistryR. C. Patel Institute of Pharmaceutical Education and Research, Shirpur (Dhule) 425405 Maharashtra India

2. Department of Pharmaceutical ChemistryH. R. Patel Institute of Pharmaceutical Education and Research, Shirpur (Dhule) 425405 Maharashtra India.

3. Department of Chemistry, Gitam School of TechnologyGitam University, Hyderabad (T.S) India.

4. Department of Pharmaceutical ChemistrySchool of Pharmacy and Technology Management, SVKM's NMIMS, (Dhule) 425405 Maharashtra India.

Funder

Indian Academy of Sciences, India

Publisher

Wiley

Subject

General Chemistry

Reference30 articles.

1. Design, Synthesis, and Anticonvulsant Activity of New Hybrid Compounds Derived from 2-(2,5-Dioxopyrrolidin-1-yl)propanamides and 2-(2,5-Dioxopyrrolidin-1-yl)butanamides

2. Secretariats of WHO/IBE/ILAE Global Campaign Against Epilepsy Atlas: Epilepsy Care in the World Programme for Neurological Diseases and Neuroscience. Department of Mental Health and Substance Abuse World Health Organization Geneva 2009. http://www.who.int/entity/mediacentre/factsheets/fs999/en.

3. Annual Report of the WHO/IBE/ILAE Global Campaign Against Epilepsy out of the Shadows Paswerk Grafish Hoofddorp The Netherlands http:// www.who.int/entity/mentalhealth/management/globalepilepsycmpaign/en.html 2003.

4. Anticonvulsant activity, crystal structures, and preliminary safety evaluation of N-trans-cinnamoyl derivatives of selected (un)modified aminoalkanols

5. Principles and Current Issues of Antiepileptic Drug Therapy

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